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Medicine

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Liver & GIT

Question
12 out of 14
 

Hera lal 35 years old man was found +ve for HBsAg & HBeAg, accidentally during screening of blood donation. On Lab examination SGOT & SGPT are Normal. What should you do next: (AIIMS Nov 07)



A Liver biopsy
B Interferon therapy

C Observation
D HBV-DNA estimation

Ans. D HBV-DNA estimation

DNA polymerase

1. It is a marker for active viral replication.

2. It is usually associated with Acute viral hepatitis B when there is active viral replication

3. DNA polymerase is often present in acute Hepatitis B infection, its presence suggests active virus replication (like HbeAg, HBV DNA) and it is not be used as a laboratory marker for acute hepatitis B infection.

Markers for HBV Replication

1. Qualitative Markers: - HBe Ag is a qualitative marker for HBV replication

2. Quantitative Markers

a- HBV DNAis a quantitative definitive marker for HBV replication

b- DNA polymerase is a definitive marker for HBV replication

Liver & GIT Flashcard List

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