Highly active antiretroviral therapy against HIV infection includes one or more nucleoside analogue reverse transcriptase inhibitors in combination with representatives of which class of antiretroviral agents?
|A||Inhibitors of viral binding|
|B||Inhibitors of viral protein processing|
|C||Inhibitors of viral release|
|D||Inhibitors of viral uncoating|
a. A growing number of drugs have been approved for treatment of HIV infections.
b. It must be remembered that all HIV drug treatments are only virostatic and not virucidal at this point in time.
c. Classes of drugs include nucleoside and nonnucleoside inhibitors of the viral reverse transcriptase and inhibitors of the viral protease enzyme.
d. The protease inhibitors are significant because protease activity is absolutely essential for production of infectious virus, and the viral enzyme is distinct from human cell proteases.
e. These inhibitors block virus entry into host cells.