Female Genital Tract
Histologic changes most characteristic of atypical hyperplasia in a post menopausal patient is (AIPG 2011)
|A||Crowding of endometrial glands with budding and epithelial atypia|
|B||Lymphatic invasion by interlacing bundles of atypical spindle-shaped cells|
|C||Menstrual – type endometrial glands with focal atypical cystic dilatation|
|D||Secretory-type endometrial glands with hyperplasia of atypical polygonal cell having clear cytoplasm|
a. Complex hyperplasia consists of crowded endometrial glands having budding, but no cytologic atypia, while atypical hyperplasia is characterized by complex glandular crowding with cellular atypia.
b. The most important prognostic feature is the presence of cytologic atypia.