Hyperparathyroidism rarely produces a condition known as brown tumor. This has to be differentiated from giant cell tumor. Which of the following histological features help in the same (AIPG 2009)
|A||In hyperparathyroidism the giant cells are smaller, often occurring in a nodular pattern especially around areas of hemorrhage|
|B||The stromal cells in hyperparathyroidism are somewhat delicate and spindle shaped|
|C||The bone surrounding the lesion shows intense osteoclastic and osteoblastic activity assoc with peri trabecular fibrosis|
|D||All of above|
All of above
In addition to a ,b, and c there is evidence of osseous metaplasia within the stroma in hyperparathyroidism.
a. Even so whenever a Diogenesis of giant cell tumor is contemplated blood chemical tests like serum calcium, phosphorus, alkaline phosphatase and estimation of parathyroid hormone levels should be made.