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Biochemistry

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Carbohydrates

Question
33 out of 40
 

Hypoxia increase glycolysis due to(AIPG 2007)



A Release of glycolytic enzyme

B 2, 3 DPG which causes activation of pyruvate dehydrogenase

C Both of the above

D None of the above

Ans. B 2, 3 DPG which causes activation of pyruvate dehydrogenase

a. Role of Hypoxia in pyruvate dehydrogenase

b. Anaerobic metabolism leads to a decrease in A TP production, thus there s - ATP-ADP ratio in hypoxic condition.

c. Pyruvate dehydrogenase is regulated by a protein kinase through serine residue on the complex (pyruvate dehydrogenase component) resulting in decreased activity.

d. This protein kinases is activated by increase in the [ATP]/[ADP], [acetylcoA]/[CoA] and [NADH]/[NAD+] ratio.

e. Under hypoxic condition, BPG is preferably converted to, BPG thus by passing an A TP generating step and hence decreasing [ATP]/[ADP] ratio.

Carbohydrates Flashcard List

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