If this patient undergoes a percutaneous coronary procedure and placement of a stent in a coronary blood vessel, she may be given eptifibatide. The mechanism of eptifibatide anti clotting action is(LQ)
|A||Activation of antithrombin III|
|B||Blockade of posttranslational modification of clotting factors|
|C||Inhibition of thromboxane production|
|D||Irreversible inhibition of platelet ADP receptors|
|E||Reversible inhibition of glycoprotein IIb/IIIa receptors|
a. Eptifibatide is a reversible inhibitor of the glycoprotein lIb/IlIa receptor, an integrin on the surface of platelets that serves as a key regulator of platelet aggregation. Glycoprotein lIb/IlIa receptor antagonists help to prevent platelet-induced occlusion of coronary stents.