In CSF, limulus amebocyte lysate assay is positive in which of the following:
|B||Gram negative meningitis|
a. Limulus amebocyte lysate(LAL) is an aqueous extract of blood cells (amoebocytes) from the horseshoe crab, Limulus polyphemus.
b. LAL reacts with bacterial endotoxin or lipopolysaccharide (LPS), which is a membrane component of Gram negative bacteria.
c. This reaction is the basis of the LAL test, which is used for the detection and quantification of bacterial endotoxins.