Oncology and Fibroids
In Leiomyoma of uterus, least likely change to occur (AIIMS Nov. 2012)
Degenerative changes in fibroid
1. Hyaline degeneration (the commonest) leads to a smoother and more homogeneous lesion, which may become cystic if liquefaction occurs.
2. Fatty changes are rare.
3. Calcification usually occurs in postmenopausal subserosal fibroids.
4. Red degeneration presents almost exclusively in pregnancy with acute pain, fever and localized tenderness. It is due to aseptic inflammation and thrombosis. It is usually managed conservatively.
5. sarcomatous degeneration is the least common The exact risk of sarcomatous change remains uncertain, but is probably 0.1 %.