In apoptosis, Apaf-1 is activated by release of which of the following substances from the mitochondria? (LQ)
|C||Bcl – XL|
Apoptosis is induced by a cascade of molecular events all of which culminate in the activation of caspases. 'In the cytosol cytochrome C binds to a protein called Apaf I (Apoptosis activating factor - 1) and the complex activates caspase 9'