Loading....
Coupon Accepted Successfully!

Biochemistry

Open Flashcards

Lipid

Question
16 out of 26
 

In electrophoresis which lipoprotein will least migrate(AIPG 2010)



A Chylomicrons
B VLDL

C LDL
D HDL

Ans. A Chylomicrons

A lipoprotein is a biochemical assembly that contains both proteins and lipids. The lipids or their derivatives may be covalently or non-covalently bound to the proteins. Many enzymes, transporters, structural proteins, antigens, adhesins and toxins are lipoproteins. Examples include the high density (HDL) and low density (LDL) lipoproteins which enable fats to be carried in the blood stream, the transmembrane proteins of the mitochondrion and the chloroplast, and bacterial lipoproteins

Lipoproteins may be classified as follows, listed from larger and less dense ones to smaller and denser ones. Lipoproteins are larger and less dense, if they consist of more fat than of protein.

a. Chylomicrons carry triglycerides (fat) from the intestines to the liver, skeletal muscle, and to adipose tissue.

b. Very low density lipoproteins (VLDL) carry (newly synthesised) triacylglycerol from the liver to adipose tissue.

c. Intermediate density lipoproteins (IDL) are intermediate between VLDL and LDL. They are not usually detectable in the blood.

d. Low density lipoproteins (LDL) carry cholesterol from the liver to cells of the body. LDLs are sometimes referred to as the "bad cholesterol" lipoprotein.

e. High density lipoproteins (HDL) collect cholesterol from the body's tissues, and bring it back to the liver. HDLs are sometimes referred to as the "good cholesterol" lipoprotein.

Density (g/ml)

Class

Diameter (nm)

% protein

% cholesterol

% phospholipid

% triacylglycerol

>1.063

HDL

5-15

33

30

29

4

1.019-1.063

LDL

18-28

25

50

21

8

1.006-1.019

IDL

25-50

18

29

22

31

0.95-1.006

VLDL

30-80

10

22

18

50

<0.95

Chylomicrons

100-1000

<2

8

7

84

Of all the lipoproteins, Chylomicrons has lowest amount of proteins, therefore lowest charge and also it has largest size making it as almost immobile in electric field

Lipid Flashcard List

26 flashcards
1)
2)
3)
4)
5)
6)
7)
8)
9)
10)
11)
12)
13)
14)
15)
16)
17)
18)
19)
20)
21)
22)
23)
24)
25)
26)