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Oncology and Fibroids

Question
3 out of 115
 

In leiomyoma of uterus which of the following changes does not occur: (AIIMS Nov 2013)



A Fatty degeneration
B Squamous metaplasia

C Hyaline degeneration
D Atrophy

Ans. B

Squamous metaplasia

Secondary Changes (Degenerations) Associated with Leiomyomas

1. Atrophy.

It occurs due to reduced vascularity

2. Hyaline degeneration

A hyaline myoma is hard and firm and it causes no specific clinical symptoms.

3. Cystic degeneration

It is seen most frequently in large intramural tumors and is best marked in the middle because the blood supply is less plentiful here.

4. Fatty changes

Most cases result from previous red degeneration

5. Red degeneration

a. Develops most frequently during pregnancy although it is not rare. in cases of painful

b. myomas in women over the age of 40. Myoma becomes tense and tender and causes

c. severe abdominal pain with constitutional upset and fever.

d. Tumor itself assumes a peculiar purple red color and develops a fishy odor.

e. Careful examination shows that some of the large veins of the capsule and the small vessels in the substance of the tumor are thrombosed. Discoloration is possibly caused by diffusion of blood pigments from the thrombosed vessels.

6. Sarcomatous changes

It is extremely rare in leiomyoma and the incidence is less than 0.5% of all myomas.

Intramural and sub-mucous tumors have a higher potential for sarcomatous change than a sub-serous tumor.

7. Torsion

a. Subserous myoma may undergo rotation at the site of its attachment to the uterus. Veins are occluded and tumor becomes engorged with blood.

b. Very severe abdominal pain is experienced and most patients are operated upon immediately. Very rarely the rotated tumor may adhere to adjacent viscera, obtain a fresh blood Supply from theses adhesions and finally be detached completely from uterus, the so called wandering fibroid or parasitic fibroid.

8. Inversion

Caused by submucous fundal myoma.

9. Capsule rupture

Very rare.

10.Inflammatory changes

Most frequently arise in submucous myomas and myomatous polypi.

Oncology and Fibroids Flashcard List

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