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Physiology

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Endocrinology

Question
14 out of 50
 

In postmenopausal women, estrogen is metabolized mostly into:



A Estriol
B Estrone

C Estradiol
D Androstenedione

Ans. B Midcycle

Circulating estrogens In the ovulating woman are derived from two sources:

  1. Sixty percent of mean estrogen formation during the menstrual cycle is in the form of estradiol Q, formed primarily by ovaries.
  2. Remainder is estrone formed mainly in extraglandular tissues from androstenedione
  3. After menopause extraglandular estrogen formation is the major pathway for estrogen synthesis Q Estrogen production by the menopausal ovary is minimal Plasma levels of estradiol are lower in postmenopausal women than levels of estrone The rate of peripheral formation of estrone increases in menopausal women so that estrone production is only slightly less than it was prior to the menopause despite the fall in plasma androstenedione. The predominant estrogen formed is ESTRONE rather than estradiol. Q

Endocrinology Flashcard List

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