Incorrect statement in pregnancy:
|A||Dose of local anaesthetic decreases|
|B||Minimum alveolar concentration decreases|
|C||Induction with inhalational agents is delayed|
|D||Chances of aspiration are very high|
|E||Intubation may be difficult|
Induction with inhalational agents is delayed
Due to increase in minute volume, induction with inhalational agents is faster and due to sedative effects of progesterone. MAC may decrease by 30%. Local anaesthetic dosage may be decreased by 30-40% due to decreased subdural and epidural spaces. So chances of high spinal are very high in pregnant patient.
Due to capillary engorgement (progesterone effect) in upper airway there may be laryngeal edema making intubation difficult.
A pregnant patient is very vulnerable for aspiration (Mendelson syndrome) because progesterone relaxes lower esophageal sphincter (LES) and delays gastric emptying. Gastric contents are also more acidic.
Secondly gravid uterus changes the angle of gastroesophageal junction making LES incompetent