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Paediatric

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Metabolic Diseases

Question
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Infant Diabetic mother with weight 3.8 Kg presented with seizures after 16 hours of birth.What is the most likely cause - (AIIMS Nov 2013)



A Hypoglycemia
B Hypoxia

C Birth Trauma
D Increased fetal defect

Ans. A

Hypoglycemia

a. Electrolyte disturbances, including hypoglycemia and hypocalcemia, are commonly seen in association with infants of diabetic mother and may result in early-onset seizures.

b. Sorry friends, I could not find any reference which has directly mentioned that hypoglycernia is a more common cause of seizure than hypocalcemia in infants of diabetic mother.

c. I was just able to find following two statements: -

"Infants of diabetic mother are most at risk for hypoglycemia which can res t in seizure".

Infant of diabetic mothers with seizures, that does not respond to glucose should have their serum calcium measured

d. From these two statements, it seems to me that hypogtycemia is a more common cause of seizures in infant of diabetic mother.

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