General Virology and DNA Viruses
Interferon is produced by cells in tissue culture when the cells are stimulated with which of the following?
a. Interferons are a family of host coded proteins produce by cell on induction by viral or nonviral inducers.
b. They alter cell metabolism to inhibit viral replication. They have no direct action on the viruses but induce the formation of a second protein that interferes with the translation of viral messenger RNA.
c. Production of interferon has been demonstrated when cells in tissue culture are challenged with viruses, rickettsiae, endotoxin, or synthetic double-stranded polynucleotides.
d. Interferon confers species-specific, not virus-specific, protection for cells.