Intractable glaucoma characteristically occurs in which one of the following? (AIPG 2010)
|A||Diffuse iris melanoma|
|B||Anterior iris melanocyte proliferation|
|C||Posterior uveal melanocyte proliferation|
1. Iris melanoma usually grows very slowly along the iris surface and may invade the angle and anterior ciliary body – intractable glaucoma.Iris melanoma makes up about 5% of uveal melanomas.
2. Conditions associated with or predispose to early onset uveal melanomas are:
a. Ocular melanocytosis
b. Nevus of Ota
c. Dysplastic cutaneous nevi
d. Familial melanoma
3. Presentation of iris melanoma is in the fifth to sixth decade, a decade earlier than ciliary body and choroidal melanoma, with enlargement of a pre-existing iris lesion.
4. Treatment –
a. Iridectomy for small tumors
b. Iridocyclectomy for tumors invading the angle
c. Radiotherapy for non-resectable tumors
d. Enucleation for diffusely growing tumors