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Biochemistry

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Purines, Pyrimidines and Nucleic Acid Metabolism

Question
45 out of 59
 

Introns are not +nt in: (AIIMS Nov 2011)



A Nuclear DNA
B Mit. DNA

C Z DNA
D B DNA

Ans. B Mit. DNA

Several unique feature of mt DNA render it venerable to mutation and contribute to its role in disease for example

mtDNA has no introns.

Depending on the base pair composition and physical condition DNA remain main conformation.

B-DNA is most common form found in cell.

Z-DNA occurs in region rich in guanine and cytosine.

Type of DNA

DNA can exist in several conformation depending upon the base composition and under different physical condition.

B-DNA

A-DNA

Z-DNA

1. Most common confirmation Q

2. Right handed helix

3. 10 base pairs per turn

1. Not found under physiological condition

2. When B-DNA crystals are dried, the long thin B-DNA becomes short, stubby A-DNA

3. Right handed helix

4. 11 bp per turn

1. Occurs in region rich in guanine & cytosine base pairs

2. Left handed helix

3. 12 BP per turn.

Purines, Pyrimidines and Nucleic Acid Metabolism Flashcard List

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