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Kidney: Blood Flow/O2 Consumption

(WEIGHT = 300 GM)

A. Renal Blood Flow
 

Total

1260 mL/min

Cortical

5 mL/Gm/min

Outer Medulla

2.5 mL/Gm/min

Inner Medulla

0.6 mL/Gm/min

 

Effective Renal plasma flow (ERPF)

Renal plasma flow (RPF) = 700 mL/min

 

B.  O2 Consumption
 

Total

18 mL/min

Cortex

9 mL/100 gm/min

Inner Med.

0.4 mL/100 gm/min


(A-V) O2 Diff. = 14 ml/L

 

Other Points

 

1.  Blood Flow

Liver >

Kidney >

Sk Msl >

Brain

 

(mL/min)

(1500) 

(1260)

(840)    

(750)

(mL/100g/min)

Kidney >

Heart >

Liver >

Brain

 

(420)

(84)      

(58)     

(54)

 

2. A-V O2 Diff

Heart >

Brain >

Sk Msl >

Liver >

Kidney

 

(mL/L)

(114)    

(62)     

(60)       

(34)       

(14)

 

3. O2 Consumption

Liver >

Sk Msl >

Brain >

Heart >

Kidney

(mL/min) 

(51)

(50)       

(46)      

(29)     

(18)

 

 

4. O2  Consumption

Heart >

Kidney >

Brain >

Liver

 

(mL/100g/min)

(9.7)

(6)

(3.3)

(2.0)

Glomerular Filtration

This is governed by the same forces (Starling’s forces) as that across capillary.

 

GFR = Kf [ (PGC - PT) + (πt - πGC)]
Where   Kf = filtration coefficient
GC = Glomerular capillary
T = Tubule
P = Hydrostatic pressure
π = Oncotic pressure
(Hydrostatic pressure is a ‘push’ force and Oncotic pressure is a ‘retaining’ or pull force)





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