Lactate is transported from muscle to Liver because
|A||Liver has mitochondria|
|B||Lactate is stored in Liver|
|C||Liver has Glucose 6 Phosphatase|
|D||Lactate is oxidized in Liver|
1. Glucose-6-phsophatase mediates the final step in glycogenolysis, and release glucose into blood from glu- 6- phosphate
2. This enzyme is present in Liver and kidney, and normally absent in muscles.
Cori’s cycle: - the lactate formed by oxidation of glucose in skeletal muscle and by RBC is transported to the liver and kidney where it reforms glucose, which again become available via the circulation for oxidation in tissues.