Loading....
Coupon Accepted Successfully!

Physiology

Open Flashcards

Respiration

Question
3 out of 33
 

Level of Hypoxia is independent of (AIIMS NOV 2010)



A Hb
B FiO2
C PCO2
D Altitude

Ans. C

a. Hypoxia is O2 deficiency at the tissue level. Traditionally, hypoxia has been divided into four types.

i. The four categories are

b. Hypoxic hypoxia, in which the PO2 of the arterial blood is reduced; so, depends on FiO2 in inspiredair.

c. Anemic hypoxia, in which the arterial PO 2 is normal but the amount of hemoglobin available to carry O2 is reduced; so, it depends on amount of Hb.

d. Stagnant or ischemic hypoxia, in which the blood flow to a tissue is so low that adequate O2 is not delivered to it despite a normal PO2 and hemoglobin concentration; and

e. Histotoxic hypoxia, in which the amount of O2 delivered to a tissue is adequate but, because of the action of a toxic agent, the tissue cells cannot make use of the O2 supplied to them.

Hypoxic

Anaemic

Stagnant

Histotoxic

Underlying cause

PaO2 is ed

Amount of available Hb decreases

O2 carrying capacity is normal but O2 delivery is decreased

No utilization at tissue level

Examples

High altitude, lung disease

Anaemic, CO poisoning

Heart failure shock hemorrhage

Cyanide poisoning

PaO2

ed

Normal

Normal

Normal

O2 Content dissolved

ed

Normal

Normal

Normal

Combined (with Hb)

ed

ed

Normal

Normal

Chemoreceptors stimulation

Stimulated (+)

Not stimulated

Strongly stimulated (+++)

Strongly stimulated (+++)

Amount of reduced Hb

ed

Total Hb ed,

% of reduced Hb ed

↑↑↑ed

ed

Cyanosis

Can be present

NEVER

Can be present

NEVER

SO, Level of hypoxia depends on Hb( anemic hypoxia), FiO2 HYPOXIC HYPOXIA) & Altitude (HYPOXIC HYPOXIA) but not pCO2. infact high p CO2 can lead to hyperventilation and increase oxygen supply.

Respiration Flashcard List

33 flashcards
1)
2)
3)
4)
5)
6)
7)
8)
9)
10)
11)
12)
13)
14)
15)
16)
17)
18)
19)
20)
21)
22)
23)
24)
25)
26)
27)
28)
29)
30)
31)
32)
33)