Autonomic Nervous Systems
Lid retraction is caused by? (AIIMS Nov 2011)
Apraclonidine is a sympathomimetic agent used in open angle glaucoma. It decreases aqueous secretion. It can result in upper lid retraction as an adverse effect. It can also result in ocular allergy (less likely with brimonidine). Both apraclonidine and brimonidine can cause CNS depression and apnea in neonates and are contra-indicated in children less than 2 years of age.