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Dermatology

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Genodermatoses

Question
9 out of 14
 

Lisch nodules are seen in: (LQ)



A Albright's syndrome
B Neurofibromatosis

C Tuberous sclerosis
D Piebaldism

Ans. B
Neurofibromatosis

1). Neurofibromas are soft papules or nodules and they invaginate into the skin with pressure in a manner similar to a hernia (the button hole sign).

2). Multiple neurofibromas, usually in combination with 6 or more cafe au lait spots measuring >1.5 cm and multiple Lisch nodules, are seen in von Recklinghausen's disease (NF type I).

3). Lisch nodules are 1-mm yellow-brown spots within the iris and are best seen on slit-lamp examination.

4). Other manifestations include axillary freckling and peripheral and CNS tumors.

Genodermatoses Flashcard List

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