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Biochemistry

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Lipid

Question
41 out of 63
 

Long chain fatty acid transported into inner mitochondria membrane by



A Acyl carrier protein
B Acyl carnitine

C Simple diffusion
D Energy mediated

Ans. B Acyl carnitine

During oxidation of Fatty acids in mitochondria: -

a. Long chains fatty acids penetrate the inner mitochondrial membrane as carnitine derivatives.

b. Carnitine is synthesized from Lysine and methionine in liver and kidney.

c. Activation of the lower acids and their oxidation within the mitochondria may occur independently of carnitine.

d. But, Long chain Acyl CoA activated Long chain fatty acids will not penetrate the inner membrane of mitochondria and become oxidized unless they from “Acyl carnitine.

e. An enzyme, carnitinepalmitoyltransferase I present in the outer mitochondrial membrane, converts long chain Acyl CoA activated F.A to Acyl carnitine, which is able to penetrate the inner

membrane of mitochondria and gain access to the β-oxidation system of enzymes.

Lipofuscin

i. Also known as “wear and tear pigment” or Aging pigments

ii. Is composed of polymers of lipids and phospholipids complexed with proteins.

iii. Particularly prominent in liver and heart of aging patients or patients with severe malnutrition and cancer cachexia

iv. Is usually accompanied by organ shrinkage ie. Brown Atrophy.

Lipid Flashcard List

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