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Pathology

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Neoplasia

Question
3 out of 24
 

Lynch syndrome is associated with cancers of the- (AIPG 2012)



A Breast, colon, ovary

B Breast, endometrium, ovary

C Breast, colon, endometrium

D Colon, endometrium, ovary

Ans. D Colon, endometrium, ovary

· Lynch syndrome is an autosomal dominant disorder

· It is also called as Hereditary Non-polyposis Colon Cancer (HNPCC) syndrome

· It is caused because of defective DNA repair genes leading to microsatellite instability.

· There is increased chance of multiple cancers (colorectal area, endometrium, ovary; stomach, ureter, brain, small intestine,
hepatobiliary tract and skin)

Neoplasia Flashcard List

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