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Pathology

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Inflammation

Question
6 out of 13
 

Major basic protein is formed by – (AIPG 2011)



A Lymphocyte
B Basophil

C Neutrophil
D Eosinophil

Ans. D Eosinophil

Eosinophil

· Eosinophils are the major participants in allergic responses and parasitic infestation.

· Eosinophils develop from stem cells in response to IL-5

· The major chemokine for eosinophils is eotaxin

· Eosinophils have a granule that contains major basic protein (MBP)

· Major basic protein has the following effect.

1. Bactericidal

2. Toxic to parasites

3. Causes degranulation of mast cells.

Inflammation Flashcard List

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