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Medicine

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Respiratory

Question
13 out of 20
 

Mantoux is negative in? (DNB June 2010)



A HIV
B Miliary TB

C Sarcoidosis
D All of the above

Ans. D

All of the above

Investigations

Tuberculin test

False negative tuberculin test –

1). Measles

2). AIDS

3). Lymphomas, Leukemia

4). Sarcoidosis

5). Protein malnutrition

6). Miliary tuberculosis,

7). TBM

8). Immunosuppressive drugs

9). Newborn & elderly

10). Live viral vaccinations

11). Defective cell mediated immunity

Tests in TB

1). Chest x – ray

2). Sputum smear – At least 2 samples

a. Zeil – Nelson technique – when bacilli are numerous

b. Auramine – phenol fluorescent – when bacilli are less

3). Sputum culture – May take 12 weeks to positive, Löffler’s medium

4). ELISA for IgG Antibodies

Recent Advances: - New technique in diagnoses of TB (Ref. Hari-18th ed., Pg- 1351)

1). IF – γ release assay (PNQ)– including, TB quantiferone Gold, T-spot TB

2). BACTEC radiometric method – 14c labelled palmitic acid can detect growth in 5 – 8 days

3). It is the only method to detect live bacilli

4). DNA probe – within hours

5. PCR

Respiratory Flashcard List

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