General Virology and DNA Viruses
Marker of relative infectivity of serum in Hepatitis B is:
a. The presence of HBeAg is a marker of active disease and infectivity. High HBeAg indicates high infectivity and low levels indicates low infectivity.
b. For example, pregnant mothers infected with HBV who have the absence of serum HBeAg, there is a greater than 10 percent transmission rate to the fetus, whereas in pregnant mothers with HBeAg in their serum, there is a greater than 90 percent transmission rate to the fetus.