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Medicine

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Liver & GIT

Question
13 out of 18
 

Massive splenomegaly is least like to occur in which of the following condition?(AIIMS May 11)



A Hairy cell leukemia

B Gaucher disease

C Essential thrombocytosis

D Portal hypertension

Hepatorenal Syndrome

Ans. C Essential thrombocytosis

Splenomegaly:

It is the most constant finding is PHT

In portal hypertension there is massive splenomegaly. At times it may causehypersplenism which can cause pancytopenia. Other causes of massive splenomegaly are

1. Chronic malaria

2. Chronic kalaazar

3. Myelo proliferative disorder

4. Hairy cell leukemia

5. Glycogenic storage disease (Gaucher disease)

Note: In all Myelo proliferative disorder which include PCV, ET and CML massive splenomegaly can occur but , however, in ET splenomegaly may not be massive.

Hepatorenal Syndrome (Ref. H-18th Edi, Pg 2601)

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