Most acceptable theory for halothane hepatitis
|A||Direct hepatocellular damage by oxidative metabolites|
|C||Hypotension due decreased cardiac output'|
|D||Direct hepatocellular damage by reductive metabolites|
All of the mechanisms stated above are responsible for causing hepatocellular damage but the most acceptable theory is immunologic because hepatitis is seen only after multiple exposures, antibodies against liver cells can be detected in serum and is more commonly. seen in patients suffering from other autoimmune diseases.