Diseases of The Middle Ear
Most accepted theory for the formation of choles- teatoma: [DNB Dec 2011]
|C||'Ingrowth of squamous epithelium|
Most common accepted theory for formation of cholesteatoma is formation of a retraction pocket. According to this theory, chronic negative middle ear pressure (which occurs due to poor Eustachian tube function and chronic inflammation of the middle ear) leads to retractions of the structurally weakest area of the tympanic membrane, the parts f/accida. Once the retractions form, the normal migra- tory pattern of the squamous epithelium is disrupted, resulting in the accumulation of keratin debris in the cholesteatoma sac.