Most common presentation of neuroblastoma is - (LQ)
|A||Lytic lesion in skull with suture diasthesis|
|D||Secondaries in brain|
Lytic lesions in skull, with sutural diastasis
a. Most frequent site of metastasisfromnueroblastoma is bone ; where ntetastasis occurs very early.
b. Lytic lesions in skull and sutural diastasis are manifestations of bony metastasis to skull, and hence the earliest feature, amongst the options in the questions.