Most common sequelae due to periventricular leukomalacia (AIIMS Nov 2013)
o Spastic diplegia is commoner in preterm babies and is associated with periventricular leukomalacia.
o Periventricular leukomalacia is a form of brain injury characterized by the death of white matter near the cerebral
o ventricles due to damage and softening of brain tissue.
o Premature infants are at the greatest risk of developing periventricular leukomalacia.
o Affected individuals develop : -
i) Motor control problems
ii) Other developmental delay
iii) Cerebral palsy (especially spastic diplegia)