General Parasitology and Protozoa
Mucocutaneous leishmaniasis: (DNB Dec 2009)
a. Mucocutaneous leishmaniasis (espundia/ chiclero ulcer) is caused by L. Brasiliensis or L.guyanensis.
b. Mucocutaneous disease is most commonly caused by New World species of Leishmania, although Old World L aethiopica has been reported to cause this syndrome.
c. Initial infection is characterized by a persistent cutaneous lesion that eventually heals, although as many as 30% of patients report no prior evidence of leishmaniasis.
d. Several years later, oral and respiratory mucosal involvement occurs, causing inflammation and mutilation of the nose, mouth, oropharynx, and trachea.