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Biochemistry

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Carbohydrates

Question
1 out of 40
 

Mucopolysaccharidoses are inherited storage diseases. They are caused by:



A an increased rate of synthesis of proteoglycans.

B the synthesis of polysaccharides with an altered structure.

C defects in the degradation of proteoglycans.

D the synthesis of abnormally small amounts of protein cores.

Ans. C defects in the degradation of proteoglycans

In mucopolysaccharidoses, synthesis of proteoglycans is unaffected, both in terms of the structure and the amount of material synthesized. The diseases are caused by a deficiency of one of the lysosomal, hydrolytic enzymes responsible for the degradation of glycosaminoglycans (not the core protein).

Carbohydrates Flashcard List

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