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Enlarged head (Megalencephaly)

  1. Due to thickened cranium
    1. Chronic anemia
    2. Rickets
    3. Osteogenesis imperfecta
    4. Epiphyseal dysplasia
  2. Due to abnormal storage of substance with in brain parenchyma
    1. Tay-Sachs
    2. Mucopolysacharidoses
    3. Maple syrup urine disease
    4. Leukodystrophies
      1. Metachromatic
      2. Alexander
      3. Canavan
  3. Due to increase brain mass
    1. Cerebral gigantism
    2. Neurofibromatosis




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