Liver & GIT
Non-parenteral hepatitis is: (AIIMS May 07)
Hepatitis Viral Families
A – Picorna
B – Hepadna
C – Flavi Viride
E - Calci
Epidemiology (Ref. Hari-18th ed., Pg 2537)
Hepatitis A – Transmitted by Feco -oral route Q. Occurs more in children Q.
Hepatitis B – Transmitted by percutaneous inoculationQ. Sexual intercourse Q and vertical transmission from mother to child.
90% of HBeAg positive mother and 10% of anti HBe positive mothers transmit HBV infection to their off spring.
The most infections occur approximately at the time of delivery Q and are not related to breast-feeding Q.
The conditions in which there is increased prevalence of hepatitis B infection are
1. Down’s syndrome Q
2. Lepromatous leprosy Q
3. Leukemia Q
4. Hodgkin’s disease Q
5. Polyarteritis nodosa Q
6. Hemodialysis Q
7. I.V. drug users. Q
Hepatitis C – The mode of transmission are percutaneous, perinatal and sexual intercourse.
Most common cause of Blood Transfusion induced hepatitis.
The perinatal and sexual route are seen in co-infection with HIV and high level viremia, the risk being 5%.
Breast feeding does not increase the risk of HCV infection.
Hepatitis D – The modes of transmission are percutaneous sexual and perinatal.
Hepatitis E – The mode of transmission is feco oral route Q.