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It is present in enzymes-Amine oxidases, Ferroxidases, Cytochrome C oxidase, Superoxide dismutase

Deficiency: Anemia, Neutropenia, Hypopigmentation of hair and skin. Vascular abnormalities Osteoporosis, Metaphyseal fraying

Generic defects in copper metabolism

  1. Menkes’ kinky hair syndrome
  2. Wilson's disease

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