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Dermatology

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Developmental Abnormalities

Question
5 out of 44
 

Ocular hallmark of pseudoxanthoma elasticum is: (LQ)



A Retinal hemorrhage
B Iritis

C Angioid streak
D Keratitis

Ans. C
Angioid streak

1). Pseudoxanthoma elasticum characterized by abnormal deposition of calcium on the elastic fibers of the skin, eye, and blood vessels. In the skin, the neck, axillae, antecubital fossae, and inguinal area are the primary sites of involvement.

2). The yellow papules coalesce to form reticulated plaques. In severely affected skin, hanging, redundant folds develop (Chicken fat appearancE..

3). Biopsy specimens of involved skin reveal swollen and irregularly clumped elastic fibers with deposits of calcium'.

4). In the eye, the calcium deposits in Bruch's membrane lead to angioid streaks and choroiditis.

Developmental Abnormalities Flashcard List

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