CNS Part- 2
Oculogyric crisis is known to be produced by all of the following drugs, except
a. Dystonias are brief or prolonged contractions of muscles that result in obviously abnormal movements or postures, including oculogyric crises, tongue protrusion, trismus, torticollis, laryngeal-pharyngeal dystonias, and dystonic postures of the limbs and trunk.
b. Other dystonias include blepharospasm and glossopharyngeal dystonia; the latter results in dysarthria, dysphagia, and even difficulty in breathing, which can cause cyanosis.
c. Acute dystonic postures or oculogyric-crisis may be relieved by parenteral administration of benztropine (2 mg intramuscularly); or diphenhydramine (50 mg intramuscularly); or diazepam (5 to 7.5 mg intravenously), to be followed by oral antidyskinetic medication for one or two days to prevent recurrent dystonic episodes.
d. Dosage adjustments of haloperidol may control these effects.