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Vocal cords paralysis

Question
27 out of 58
 

Of the following statements about Recurrent Laryngeal papillomatosis are true, Except



A Caused by Human Papilloma Virus (HPV)

B HPV6 and HPV11 are most commonly implicated

C HPV6 is more virulent than HPV11

D Transmission to neonate occurs through contact with mother during vaginal delivery

Ans. C HPV6 is more virulent than HPV 11:

Nelson's pediatrics 7 8thl7 772; Current Otorhinology 2ndled pg-4351477 'Pediatric ENT' by Graham. Scadding and Bull (2008) 1258

Recurrent Laryngeal Papillomatosis I Recurrent Respiratory Papillomatosis

Etiology

Associated with Human Papilloma Virus infection (HPV)

HPV6 and HPV 11 are most commonly associated with laryngeal disease whereas HPV 16 and HPV 18 are less commonly associated.

HPV11 is associated with a more aggressive disease and makes the patient more prone to malignant change

Thus HPV 11 is more virulent

Epidemiology

Most commonly occur in children <5 years of age (2 -5 years)

Male female ratio - same (first born vaginally delivered child of a teenage mother is most prone)

Transmission

Exact mode of transmission is not known.

There is recognized transmission from genital warts.

Vertical transmission of virus from mother to child can occur either as ascending uterine infection or through direct contact in birth canal.

ALSO KNOW

Malignant transformation in a case of papilloma occurs most commonly in distal bronchopulmonary tree and prognosis is univer¬sally poor

Vocal cords paralysis Flashcard List

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