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Pathology

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Miscellaneous

Question
2 out of 28
 

Oil red O-positive material seen in the small blood vessels of the lungs and brain of a patient with neglected fracture of long bone suggests? (AIIMS Nov 2012)



A Air emboli
B Embolism from DVT

C Fat emboli
D Paradoxical emboli

Ans. C Fat emboli

a. An embolus is a detached intravascular mass that has been carried by the blood to a site other than where it was formed.

b. Most emboli originate from thrombi (thrombotic emboli), but they can also originate from material other than thrombi (non thrombotic emboli).

c. Types of nonthrombotic emboli include fat emboli, air emboli, and amniotic fluid emboli.

d. Fat emboli, which result from severe trauma and fractures of long bones, will stain positively with an oil red O stain or Sudan black stain.

e. They can be fatal as they can damage the endothelial cells and pneumocytes within the lungs.

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