One of the following statements regarding mycophenolate mofetil is INCORRECT (AI 2011)
|A||It is a prodrug|
|B||It is a selective, uncompetitive and reversible inhibitor of IMP dehydrogenase|
|C||It inhibits calcineurin|
|D||Selectively inhibits lymphocytic proliferation|
Mycophenolate mofetil is a prodrug. It is converted to mycophenolic acid that inhibits the enzyme, IMP dehydrogenase.
It selectively inhibits the proliferation of lymphocytes and acts as an immunosuppressant agent.
Calcineurin inhibitors are cyclosporine and tacrolimus.