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Physiology

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Endocrinology

Question
12 out of 14
 

Osteomalacia is associated with:              



A Decreases in osteoid volume       

B Decreases in osteoid surface

C Increase in osteoid maturation time

D None of the above

Ans. C Increase in osteoid maturation time

Osteomalacia is characteristically described as a 'mineralisation disorder' manifested exclusively by defect in mineralization of newly forming bone.

Abnormal minieralization / decrease in deposition of mineralized bone (i.e. decrease in mineratzation apposition rate)

Matrix continues to be secreted but is not mineralized.

(i.e. osteoid does not mature or increased osteoid maturation time)

­Increased thickness of osteoid

Increased volume of osteoid

Increase is bone surface covered by osteoid.

Endocrinology Flashcard List

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