Osteomalacia is associated with:
|A||Decreases in osteoid volume|
|B||Decreases in osteoid surface|
|C||Increase in osteoid maturation time|
|D||None of the above|
Osteomalacia is characteristically described as a 'mineralisation disorder' manifested exclusively by defect in mineralization of newly forming bone.
Abnormal minieralization / decrease in deposition of mineralized bone (i.e. decrease in mineratzation apposition rate)
Matrix continues to be secreted but is not mineralized.
(i.e. osteoid does not mature or increased osteoid maturation time)
Increased thickness of osteoid
Increased volume of osteoid
Increase is bone surface covered by osteoid.