PAH (para-aminohippuric acid) clearance is indicated by which of the following:
|A||Renal plasma flow|
|D||Glomerular filtration rate|
I. The kidneys get 1.2-1.3 liters (25 %of cardiac output) of blood per minute.
II. Renal blood flow can be measured by electromagnetic flow meters or by application of Fick’s principle which states that ‘blood flow equals the amount of a substance absorbed or excreted by an organ (or whole body) per unit time, divided by the arteriovenous difference of that substance across the organ’.
III. Renal plasma flow is generally measured by injecting PARA-AMINO-HIPPURIC ACID (PAH) and then determining its urine and plasma concentrations.