Medical and Surgical Complications in Pregnancy
Perinatal transmission of hepatits B is maximum when infection in mother occurs in (DNB, Nov. 2008)
1. Hepatitis B virus is transmitted by parentral route, sexual route, vertical transmission and also through breast milk the risk of transmission to fetus ranges from 10% in 1st trimester to 90% in 3rd trimester and it is especially high from those mothers who are seropositive to HbsAg and HbeAg.
2. All pregnant women should be screened for HBV at the first antenatal visit.
3. As incubation period of HBV is 1 to 6 mths it will take a long time to develop immunity in mother against HBV. Hence when the infection in mother occurs in 3rd trimester, only infection without immunity is transferred to fetus.