Permethrin is useful in: (AIIMS Nov 2014)
1). The treatment of choice of scabies for children 8 weeks and older is permethrin 5% cream which should be applied once to the entire skin area, avoiding the eyes, nose, and mouth. The cream should be thoroughly washed off after to 10 hours of application.
2). The fingernails should be trimmed to prevent the harboring of mites.
3). For adults, permethrin, 5% cream or lindane 1 % lotion is applied thinly and thoroughly behind the ears and from the neck down after bathing and left on overnight for 8 to 14 hr and are then removed with soap and water.
4). Lindane is absorbed through the skin, and its overuse may cause seizures and aplastic anemia.
5). Alternatives include topical crotamiton cream, benzyl benzoate, and sulfur ointments.
6). Pregnant women and infants less than 2 months of age should be treated with 6% to 10% precipitated sulfur in petrolatum daily for 3 days.
7). Successful treatment of crusted scabies requires the application first of a keratolytic agent such as 6% salicylic acid which improve the penetration of scabicides and then followed by application of scabicides to the scalp, face, and ears.
8). A single oral dose of ivermectin (200 ïg/kg) effectively treats scabies in otherwise healthy individuals. Ivermectin can be used topically in a dose of 0.8% solution.
9). IT should not be given to <5 yrs of age.