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Pathology

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Miscellaneous

Question
6 out of 28
 

Phagocytes in CNS is: (AIIMS May 2012)



A Astrocytes
B Oligodendrocytes

C Ependyma
D Microglia

Ans. D Microglia

Nerve cells (Neuroglia)

a. Astrocytes

i. Have foot processes or end feet (end on blood vessel)

ii. In damaged brain act like fibroblast and form glial "scars" (help in repair)

iii. Maintain blood brain barrier

iv. Contain GFAP (vimentin)

v. Rosenthal fibres (in juvenile pilocytic astrocytomas)

vi. Corpora amylacea (poly glucosan bodies)

vii. Lafora bodies (in myoclonus epilepsy)

b. Oligodendrocytes:

i. Maintain and produce CNS myelin

ii. Counterpart of schwann cells

iii. Also called satellite cells

iv. Cytomegalovirus makes ependymal cells the target of infection

c. Microglia

i. Microglia cells are capable of assuming the shape and function of macrophages (gitter cells:compound granular corpuscles)

ii. It is representative of mononuclear phagocyte (MPS)

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