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Microbiology

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Clinical/Applied Microbiology

Question
41 out of 45
 

Pili act as a Microbial ligand in all of the following except ?



A Neisseria
B E. coli

C Pseudomonas
D L. pneumophila

Ans. D Legionella pneumophila

Examples of Microbial Ligand-Receptor Interactions

Microorganism

Type of Microbial Ligand

Host Receptor

Viral Pathogens

Influenza virus

Hemagglutinin

Sialic acid

Measles virus

Vaccine strain

Hemagglutinin

CD46/moesin

Wild-type strains

Hemagglutinin

Signaling lymphocytic activation molecule (SLAM)

Human herpesvirus type 6

?

CD46

Herpes simplex virus

Glycoprotein C

Heparan sulfate

HIV

Surface glycoprotein

CD4 and chemokine receptors (CCR5 and CXCR4)

Epstein-Barr virus

Envelope protein

CD21 (=CR2)

Adenovirus

Fiber protein

Coxsackie-adenovirus receptor (CAR)

Coxsackievirus

Viral coat proteins

CAR and major histocompatibility class I antigens

BACTERIA

Neisseria spp.

Pili

Membrane cofactor protein (CD46)

Pseudomonas aeruginosa

Pili and flagella

Lipopolysaccharide

Asialo-GM1

Cystic fibrosis transmembrane conductance regulator (CFTR)

Escherichia coli

Pili

Ceramides/mannose and digalactosyl residues

Streptococcus pyogenes

Hyaluronic acid capsule

CD44

Yersinia spp.

Invasin/accessory invasin locus

1Integrins

Bordetella pertussis

Filamentous hemagglutinin

CR3

Legionella pneumophila

Adsorbed C3bi

CR3

Mycobacterium tuberculosis

Adsorbed C3bi

CR3; DC-SIGNa

FUNGI

Blastomyces dermatitidis

WI-1

Possibly matrix proteins and integrins

Candida albicans

Int1p

Extracellular matrix proteins

PROTOZOA

Plasmodium vivax

Merozoite form

Duffy Fy antigen

Plasmodium falciparum

Erythrocyte-binding protein 175 (EBA-175)

Glycophorin A

Entamoeba histolytica

Surface lectin

N-Acetylglucosamine

Clinical/Applied Microbiology Flashcard List

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