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Physiology

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Endocrinology

Question
36 out of 50
 

Prolactin secretion is decreased by



A Dopamine
B PRL

C TRH
D All of the above

Ans. A Dopamine
  1. Dopamine is the primary neuroendocrine inhibitor of the secretion of prolactin from the anterior pituitary gland.
  2. Dopamine produced by neurons in the arcuate nucleus of the hypothalamus is secreted into the hypothalamo-hypophysial blood vessels of the median eminence, which supply the pituitary gland.
  3. The lactotrope cells that produce prolactin, in the absence of dopamine, secrete prolactin continuously; dopamine inhibits this secretion.
  4. Thus, in the context of regulating prolactin secretion, dopamine is occasionally called prolactin-inhibiting factor (PIF), prolactin-inhibiting hormone (PIH).

Endocrinology Flashcard List

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