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Introduction

 
Nucleoside =
Nitrogenous base (purine or pyrimidine) + Pentose sugar(PG1olO) (ribose or deoxyribose)

Nucleotide = Nucleoside + phosphate group (phosphoric acid)

                                                                 or

               = Nitrogenous base + Pentose sugar + Phosphate group
 

Different major bases with their corresponding nucleosides and nucleotides
 

Base

Ribonucleoside

Ribonucleotide

Adenine (A)

Adenosine

Adenosine monophosphate (AMP) (PG109)

Guanine (G)

Guanosine

Guanosine monophosphate (GMP) (PG109)

Uracil(U)

Uridine

Uridine monophosphate (UMPYPG109)

Cytosine (C)

Cytidine

Cytidine (Monophosphate) (CMP)

Base

Deoxyribonucleoside

Deoxyribonucleotide

Adenine

Deoxyadenosine

Deoxyadenosine monophosphate (dAMP)

Guanine

Deoxyguanosine

Deoxyguanosine monphosphate (dGMP)

Cytosine

Deoxycytidine

Deoxycytidine monophosphate (dCMP)

Thymine

Deoxythymidine

Deoxythymidine monophosphate (dCMP)

 

Purines and Pyrimidines are heterocyclic ring compounds which means they have a ring of atoms containing both

carbon and non carbon (hetero) atoms.


The principle derivative of purine and pyrimidine are nucleoside and nucleotide.


Nucleic acids contain five major hetero cyclic bases: Adenine, Guanine, Cytosine, Uracil and Thymine.

Adenine and Guanine are Purines.


Cytosine, Uracil and Thymine are Pyrimidines.


Nucleoside contain sugar, D-ribose or 2-deoxy-D-ribose

Nucleotides are nucleosides phosphorylated on hydroxyl group of sugar.






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